Stillpoint Integrative Men’s Health
Testosterone and Prostate Cancer: What the Research Really Says
Does testosterone cause prostate cancer?
No—current evidence shows that testosterone replacement therapy (TRT) does not increase the risk of developing prostate cancer.
While early lab research suggested testosterone could stimulate cancer cell growth, large human studies have found no such link.
In fact, several studies suggest that low testosterone may be associated with higher prostate cancer risk or severity.
Many men hesitate to start testosterone replacement therapy (TRT) because they’ve heard it might raise their risk of prostate cancer. This idea has persisted for decades—but modern research tells a very different story.
The Origin of the Fear
Early laboratory studies found that testosterone could accelerate prostate cancer cell growth in a petri dish.
This led to the assumption that higher testosterone levels must fuel prostate cancer.
However, what happens in the lab doesn’t always reflect what happens in the human body. Over the past two decades, large-scale studies have repeatedly challenged this old belief.
The Current Evidence: No Increased Risk
The overwhelming majority of modern research shows that TRT does not increase prostate cancer risk.
While a few older studies hinted at a connection, they were often poorly designed and failed to control for other variables such as age, obesity, and genetics.
In fact, many newer studies show the opposite—that men with lower testosterone levels may have a higher risk or greater severity of prostate cancer.
- Haider et al., 2014: A five-year follow-up found that men on TRT had a lower incidence of prostate cancer compared to men who were not treated.
- University of Washington, 2018: Researchers analyzed 147,000 veterans with low testosterone. Of the 58,000 who received TRT, there was no increased rate of prostate cancer over eight years of follow-up.
These findings strongly suggest that restoring testosterone to healthy levels is safe when properly monitored.
Why Testosterone Got a Bad Reputation
The original fear traces back to treatments for advanced prostate cancer that lowered testosterone to slow tumor growth.
From that logic, doctors assumed the reverse—raising testosterone—must increase risk.
But more recent data shows that once testosterone reaches normal physiological levels, the prostate appears to be saturated, meaning extra testosterone does not promote further growth.
Monitoring for Safety
At Stillpoint Integrative Psychiatry & Wellness, we combine the latest research with rigorous monitoring.
Before beginning TRT, we check your prostate-specific antigen (PSA) levels. These are reassessed at 6-9 weeks, then every 2–3 months to ensure your prostate health remains stable throughout treatment.
This proactive approach allows you to enjoy the benefits of optimized testosterone while keeping safety front and center.
The Benefits of Balanced Testosterone
When testosterone is restored to healthy levels, men commonly experience:
- Improved mood, focus, and motivation
- Enhanced libido and sexual performance
- Better muscle tone and fat metabolism
- Increased overall energy and vitality
Low testosterone affects not only physical performance but also mental health and emotional stability. Correcting it can transform how you feel and function day to day.
Bottom Line
Modern evidence is clear: testosterone replacement therapy does not cause prostate cancer.
When guided by careful medical supervision and regular PSA monitoring, TRT can be a safe and effective treatment for men seeking renewed energy, strength, and confidence.
If you’re ready to explore testosterone therapy safely and holistically,
contact Stillpoint Integrative today for a consultation.
Your well-being—and your prostate health—are always our top priorities.
To understand how testosterone therapy fits safely within a holistic men’s health approach, visit our Testosterone Optimization Therapy overview page.
Frequently Asked Questions About Testosterone and Prostate Cancer
Does testosterone replacement therapy cause prostate cancer?
No. Current research shows that testosterone replacement therapy (TRT) does not increase the risk of developing prostate cancer. Large studies in men receiving TRT have found no higher incidence of prostate cancer compared to those who were not treated.
Can men with prostate cancer take testosterone?
Traditionally, men with prostate cancer were advised to avoid TRT. However, newer evidence suggests that in carefully selected cases—especially after successful treatment and remission—testosterone therapy may be considered under close medical supervision. Always consult a specialist before starting therapy.
How does Stillpoint Integrative Psychiatry monitor prostate health during TRT?
We monitor your prostate-specific antigen (PSA) levels before starting TRT, then again at 6 weeks and every 2–3 months thereafter. This ensures your treatment remains both safe and effective, with early detection of any potential changes.
What are the main benefits of testosterone therapy?
TRT can improve mood, energy, libido, muscle tone, and focus. It also supports metabolic and cardiovascular health when properly prescribed and monitored. Many men report better vitality and overall well-being after restoring healthy testosterone levels.